An intense drama on the portrayal of brotherhood, BROTHERS depicts the mistrust and feud between two brothers through the eyes of an investigating police officer. Despite their close relationship, Yiu and Shun were separated at a young age due to a decision made by their father. Years later they meet again when the family runs into crisis where Yiu, inspired by his father's last words, manipulates a series of setups which endangers Shun's life, so as to achieve his goal. The crisis brings the two brothers back together again. However, a series of setups arranged by Yiu causes Shun to flee to Thailand, accompanied by confidantes Ching (Crystal Huang) and Ghostie (Wong Yat-wah). As Shun is caught between life and death, the trust between the brothers is put to a serious test. When Shun finally realizes the true intention of his brother, things are already beyond repair.