Freak (1998)

John Leguizamo's semi-falsified, one-man stand-up performance as...himself. This is his autobiographical story, about his life growing up, and his journey to try to be accepted by his father. We see this story through a bizarre myriad of characters and situations, which include the eccentric Uncle Sanny, the Fat Boy Called Bitch (John's little brother, Poochie), his mom, his evil grandmothers, and Lee Stratsberg, not to mention a brief appearance by Cantinflas as God.