With the company on the brink of bankruptcy, the defiant president Echizen plans to do something foolish one last time. He sets up a lab he calls the "Orgasm Research Institute" and begins research into ecstasy with the researchers he has gathered. First, there is the interaction between Teruha, nicknamed "the 10,000-slayer" who charms men with sex, and Youji, who has a big dick. The excitement of the researchers reaches its peak when they see this. Then, they take turns to conduct dizzying experiments on pleasure in the isolation facility! What on earth lies ahead?!

Nami is a freelance nursing care helper who will do anything for her caregiver. At the request of Nagara, who runs a women-only share house, Nami visits his house, where she meets Kyoko, a legendary mat player, and Sayaka, a woman who drives men crazy with her gaze. The three strongest people come together and improve each other's skills and sensitivity, but...

Honoka, a daughter who takes care of her self-proclaimed depressed father-in-law, ran out of the house because she could not stand being sexually demanded. On the other hand, a young wife, Haruka, who got married with an age difference, also left home in a rage at her husband's behavior. Such two people meet and hit it off from each other's circumstances. They complain that they don't want to go home...