Dustin and Gary are forced to navigate their way through a modern myth when Dustin is bitten by a radioactive chihuahua. Once a curse takes hold of Dustin, he and Gary are forced to run for their lives from the monster slayer, Van Helsing.

The small town of Uranus has been invaded. Two best friend and fudge-packing employees at the Uranus Fudge Factory now must save Uranus and stop an evil hive-mind Alien slug named Zamik before he "ass-similates" all of Uranus.