Sex with Sue explores the life and career of radically progressive sex educator Sue Johanson, whose radio and TV programs offered comprehensive sex education from a pleasure-driven, feminist perspective.

Three scientists are preparing three beautiful androids to get approval for mass production from a major investor. The androids are known as "trandroids," which is short for "transformative androids," and are meant to be perfect platonic companions. But the scientists are thrown a curveball when their investor requests that the trandroids be made into romantic companions instead.