Every summer, hot bodied young singles flock to a hidden, hedonistic island just off the coast for a getaway where anything goes. But when a mad scientist sets up shop at one of the island's exclusive resorts to test out his new hypno drug, things really heat up for our horny heroes and heroines. Greed and global domination meet grunting, groping and gyrating in an orgy of - orgies in this titillating tale of terror in a two-piece. Will love save the day? Or will it plunge us ever deeper into this amorous Armageddon - this spandex epidemic of pandemic proportions - this - Bikini Apocalypse.

Samantha Vance inherits the Tiki Hotel when her father dies. She decides to fix it up but has problems drumming up business. Her friends throw a party at the hotel and an idea is born to make it the "Bikini Hotel" with all of the staff members wearing bikinis. This elicits jealousy in the nearby Regent Hotel who wish to turn Samantha's hotel into a parking lot. It all culminates in a competition where the winner gets to stay.

Mean and domineering Jane and the sweet and ditsy Jackie are two radically contrasting sisters who suffer from severe trauma after witnessing the murder/suicide of their parents as well as seeing their other sibling Janice raped and killed by her assailants. The pair are deemed fit to re-enter society and get released from a sanitarium where they have undergone extensive rehabilitation therapy. However, Jane and Jackie prove to be anything but sane and harmless as they embark on a vicious spree in which they torture, murder, and mutilate any man luckless enough to cross their lethal paths.