Jairo, who was born without nipples, is isolated from both the customs of his people and social norms. Distanced from the customs of his people, he explores in the city a male ideal to belong to.

The epic story of the first contact, encounter, approach, betrayal and, eventually, life-transcending friendship, between Karamakate, an Amazonian shaman, last survivor of his people, and two scientists that, over the course of 40 years, travel through the Amazon in search of a sacred plant that can heal them. Inspired by the journals of the first explorers of the Colombian Amazon, Theodor Koch-Grunberg and Richard Evans Schultes.