L'odyssée irréversible est un documentaire rétrospectif avec des interviews de Gaspar Noé, des acteurs Monica Bellucci, Vincent Cassel et Albert Dupontel.

Murphy is an American living in Paris who enters a highly sexually and emotionally charged relationship with the unstable Electra. Unaware of the seismic effect it will have on their relationship, they invite their pretty neighbor into their bed.