Two couples have their destinies intertwined after their happiness is unexpectedly interrupted. This is the starting point of the telenovela, which shares the same name as the São Paulo neighborhood where the story takes place. Solano Xavier is a man of humble origins who never had the chance to obtain a formal education. Unemployed for months, he celebrates with his wife Eugênia the fact that he has landed a temporary job as a truck driver. She reciprocates the good news by telling him she is pregnant. Solano, however, falls victim to a trap: unknowingly, he is transporting contraband goods on one of his trips. Detained by the police, he is arrested, tried, and sentenced to 17 years in prison. Throughout the telenovela, Solano discovers that Arthur is the main person responsible for the scheme that led to his imprisonment.

The series tells the story of a criminal investigation into the murder of businessman Paulo Gomes de Aguiar at the beginning of August. In the midst of the Vargas government crisis, the murder case is taken by police commissioner Alberto Mattos, an honest and incorruptible man who is not well regarded by his co-workers, as the place is totally turned over to corruption.

Luiza is an architect who just got out of a ruinous relationship. Gabriel is a biologist and he has finished a long marriage with divorce. When they both meet, chances that they can do well together are not that big. But they will try to, even if their friends Barata (a convict bachelor totally skeptical when it comes to love) and Marta (a mathematic analyst who wishes that human relations were just as exact as numbers are) think otherwise.

Daniel, art professor, has a car accident which results into a paranoia. He gets better, falls in love with one of his students and they decide to move away from civilization to the house in the mountains. Their peace and quiet is disrupted by three men building a road nearby. They rape the girl, beat the husband and drown their child. What will Daniel do now? Will he get his revenge? Will his past affect him?