A brilliant but troubled young man is thrust into a dark underworld when he becomes a pawn in a brutal struggle between two drug lords for a new street drug called LOCO. Alex's only hope comes from a beautiful girl who is also caught up in the scheme, and together they try to escape their dangerous world. A shocking surprise awaits them...because nothing is what it seems to be in the world of LOCO.

After thugs brutalize a deaf-mute woman, the spirit of an Apache warrior takes over her lifeless body and sets out on a bloodthirsty quest for revenge.