After releasing the Chupacabras, Leo San Juan decides that it is time to return together with his brother Nando to his grandmother's house. Halfway down the road, Charro Negro manages to confuse Leo and because of him, an innocent girl is dragged into the underworld. Leo is forced to repair the damage. His friends will come to try to help him and get out of there as soon as possible. But it is no coincidence that the Charro has chosen to involve Leo, his intentions go beyond getting a new soul.

Three friends confront a horde of mummies, who have inexplicably awakened, and try to rescue their pal, not realizing they have fallen into a trap.

Leo San Juan and his team of "ghostbusters" continue with their adventures, this time fighting against the mexican monster himself: "El Chupacabras".