Jonathan Ecks, an FBI agent, realizes that he must join with his lifelong enemy, Agent Sever, a rogue DIA agent with whom he is in mortal combat, in order to defeat a common enemy. That enemy has developed a "micro-device" that can be injected into victims in order to kill them at will.

A hit man named Kai flies into Bangkok, gets a gun, and orders a cab. He offers a professional female driver big money to be his all-night driver. But when she realizes Kai is committing brutal murders at each stop, it's too late to walk away. Meanwhile, an offbeat police detective races to decode the string of slayings before more blood is spilled.