After Cacopoulos manages to save himself from being hung on a false charge, he robs Cat Stevens and Hutch Bessy of a lot of money and steals their horses. This results in a merry chase and Stevens and Bessy become unwilling allies in Cacopoulus' revenge against the people who deserted him and framed him to get their money back.

Rome, 1825. Bishop Rivarola and Colonel Nardoni are in charge of suppressing the liberal revolution. Shoemaker Cornacchia got the information that the liberal Filippo Spada is a spy and is going to denounce his revolutionary companions.

Story of an ambitious young doctor through unethical means intend to make a quick career. Now is primary in a luxury clinic where administers the sick with the same cynicism of his young years.