Tenshu is imprisoned and sentenced to death for murdering the men who raped his girlfriend. However, he manages to survive his execution and is presented with an option: face another execution attempt or subject himself to their bizarre and dangerous experiments.

Portrait of the Wind centers on Tamio Murase, a world-traveling photographer who came home to take over the family business after his father’s fatal heart attack. One day at the family photo studio, he finds a kindred spirit in Ayako and the requisite sparks fly between them. The initial portions of the film deal with their budding romance, and it isn’t long before the two become a serious couple, and Ayako is pregnant with Tamio’s child.

A.D. 2015: A virus has been spreading in many cities worldwide. It is a suicidal disease and the virus is infected by pictures. People, once infected, come down with the disease, which leads to death. They have no way of fighting against this infection filled with fear and despair. The media calls the disease the "Lemming Syndrome".

On a cold Monday morning, a group of counselors clock in at an old-fashioned social services office. Their task is to interview the recently deceased, record their personal details, then, over the course of the week, assist them in choosing a single memory to keep for eternity.