This hyper-intersectional film is an amalgam of sci-fi creature-flick, campy music video, grotesque comedy, agitprop flick against heterocentric research as well as (soft-)pornographic subversive statement. "FUDLIAKS! Tear the sexes apart!" is set in an undefined present, in a mysterious laboratory: the Institute for Gender Normalization. The research subject of this neo-conservative think tank: the scientific underpinnings of conventional heteronormative bodies and biologically binary genders. But a new research series turns all that on its head!

In this drama, a traveling troupe of actors find themselves in danger of becoming unemployed when their manager up and leaves. Two of the actors decide to marry and settle down. The lead actor helps set up the rest of the troupe with some performances. He then destroys the new marriage. Later the woman and the head actor fall in love. He then gives her the lead role in his newest show.

An escaped convict and the detective tasked with hunting him down end up working in parallel to clear the convict's name and nab the gangsters that framed him.