Instead of fighting over newly-gained money from a coach-robbery, two gangster-brothers (El Bedoja and Chiuchi) decide to rob a bank together. But Martinez, a gangster-coward, is successfully questioned by Nigros (a clad-in-black gangster-killer who collects the money) and Rocco (a righteous ex-sheriff who doesn't and shows off even more skill in using his pistol) on their plans. After robbing the bank and needlessly shooting several townsfolk, the gangsters hide out in a mine, taking beautiful Maruja as a hostage. Although Rocco and Nigros follow different paths (Nigros the money, Rocco justice), they unite to get the money. They hire Esplotion for the explosives. Because Rocco is out of ammunition, he impales one of the gangsters with a wooden stake. A second showdown plays out in a barn.

A group of tourists arrive to see the botanical gardens on a small island off the Italian coast. The only inhabitants of the island are the famous botanist Baron von Weser and his two faithful servants; all of the other residents fled after a series of mysterious deaths. When the car driven by the tourists' guide hits one of the baron's servants, von Weser explains that the death was due to a rare and incurable disease, not the accident. That night, the guide and Cora Robinson, one of the guests, are found murdered with all the blood drained from their bodies.

Seven beautiful women in a high security prison set the stage for a big bust out.