A terminally ill old lady who wants to die on her own terms convinces a self-destructive addict to help kill her, in exchange for clean urine.

Though a childhood bout with polio left him dependent on an iron lung, Mark O'Brien maintains a career as a journalist and poet. A writing assignment dealing with sex and the disabled piques Mark's curiosity, and he decides to investigate the possibility of experiencing sex himself. When his overtures toward a caregiver scare her away, he books an appointment with sex surrogate Cheryl Cohen-Greene to lose his virginity.