Two buddies' road trip is halted by car trouble in the middle of nowhere; they stumble on a derelict hotel and are inspired to try to restore it, with the help of an odd bunch of locals.

The film tells two stories apparently very distant are slowly approaching each other. On the one hand is Babarimisa, a young man from Benin who suffers from a relentless disease for which seems to have no remedy. Desperate to save his mother, Morenike, a Yoruba priestess goes to invoke the power of the Orishas gods. Meanwhile in Argentina, Shantas is a young offender living in a marginal area tainted by the practices of Umbanda, a cult derived from African religions. None of us can even imagine the surprises that come in the destination.

Pablo is a former professional skier retired due to a health problem, who lives with Martín, his son. To celebrate his son's birthday, Pablo takes him to Sierra Nevada, Spain where they will meet Ángela and Vicky, mother and daughter respectively, where a friendship and something more will emerge.

Mora and Roberta, an Argentinean lesbian couple, are desperate to have a child. With no scruples and hesitation they work out a plan; Roberta will seduce and have sex with Felipe, Mora's brother. Felipe is a hermit who lives in Patagonia earning his living artificially inseminating turkeys. Sure enough, things won't go smoothly. Felipe isn’t easily seduced, and when an unexpected visitor turns up – with surprising news -- everyone will get more than he/she has bargained for!

Three people and a baby set off on separate journeys, along the same road; their disparate dreams and stories intertwine amidst the breathtaking deserted Patagonic route.