Dusty Gardner, and other Texas ranchers, are driving a herd of cattle to Abilene, Kansas along the Chisholm Trail. Desperate need of water takes them to the Turner ranch, where Belle Turner demands exorbitant prices for the water. Dusty learns that Belle is also trying to oust Mary Lee and Montana Smith from the trading post Mary operates. The sheriff sides with Belle following a fight between the two women. Belle knows there is artesian springs under the land the trading post occupies and intends to get the property by any means.

Unknown to Joan Manning, her trading post partner Weathers is operating a counterfeiting ring. When miner Jim Smithers brings his gold dust in, Weathers pays him off in counterfeit money. Jim's drunken brother, Bill, comes to the post and Weathers hears him say that Jim is leaving the area for good. Weathers sends Hawks to kill Jim and retrieve the bogus money. RCMP Sergeant Renfrew and Constable Kelly find Jim's body, and Renfrew hurries for Jim's cabin to search it. He is attacked by Weathers' men who have found the money. Renfrew is suspicious when Bill Smithers body is found, supposedly a suicide, with a note he had burned the money. This leads the Mounties to suspect counterfeiting. Kelly follows Manti, an Indian who works for Weathers, to the gang's hideout and is captured. But Renfrew is trailing Kelly.

Hammond is after the Craig ranch and has framed Charlie Craig for murder. Mother Craig brings in the Range Busters. They capture one of Hammond's men and Alibi plans to trick him into a confession as to who the real murderer is. Meanwhile, Denny has overheard Hammond's plans for his next move and he and Crash set out to round up the gang.

El Puma, a Mexican desert guide, escorts an archaeological expedition headed by Professor Lucius Lloyd through the Indian badlands of Mexico. Marian, the professor's niece accompanies the party as only she can translate the Aztec writings in the diary of her father, murdered on a similar expedition six years previous. The professor is murdered by a knife, and the weapon is recognized as the property of El Puma. Magpie, a Federal Investigator, knows that El Puma is really "Lightnin' Bill' Carson, a former federal agent who has been missing since Marian's father was slain. The reluctant Magpie believes that his old pal is guilty. Carson sets out to prove otherwise.

A man accused of planning a prison break turns the tables on escaped cons by leading the group into the desert.

A white gorilla causes trouble in the deepest heart of Africa. The film uses footage from the silent 1927 serial Perils Of The Jungle.

Head over heels in love with a stern and cold older businessman's young wife, a reporter is seduced into conspiring to murder him so she can inherit his estate, while pinning the murder on another businessman.

A demented archaeologist discovers a living, breathing serpent creature known to the Aztecs as Quetzalcoatl and accidentally kills his wife by giving her one of the beast's feathers, causing the creature to track her down and slaughter her. Using this knowledge he exacts revenge upon his enemies by placing one of the feathers on his intended victim and letting the beast loose to wreak havoc.