Cécile, Annette, Yvonne, Émilie and Marie, the Dionne Quintuplets, turn five years old and have a private birthday party in their garden. Other than the five little French-Canadian princesses-of-the-world, the attendees at the party for the sheltered sisters are their doctor-and-mentor Roy Dafoe; a priest and two nurses; radio's "Town Crier" Alexander Woollcott; and RKO-Newsreel cameraman Harry Smith.

Rival reporters compete to sign the Wyatt Quintuplets to be guests on their radio shows.