In an attempt to cope with her sister's death, Sarah joins a sorority. However, as her new sisters begin to manipulate her, she becomes trapped in their devious plans and has to fight to maintain her innocence.

Between working full-time, raising a young son, and trying to maintain a relationship with her detached husband, James, Lauren Bell desperately needs some help in watching her newborn, Riley. Thinking she's found the perfect solution, she hires her neighbor, Owen, to be their nanny. Owen is exactly what the Bells need and Lauren couldn't be happier. It isn't long, though, until Owen crosses the boundaries between hired help and man of the house.

Finding his daughter confused and drunk one night, Martin overreacts and puts a wedge between their once idyllic relationship at a time when she'll need him the most.

Linda has a seemingly perfect marriage with her rugged and handsome husband Mark and an adorable 8 year old daughter, Chloe. But when Chloe is injured by an elderly babysitter who has slipped into dementia, Linda wants to ensure that her child is never hurt again. Initially, Heather, the new babysitter, seems like the ideal addition to this practically perfect family. But Heather is a schemer who exploits the cracks in Mark and Linda's relationship, and delights in the resulting chaos. As Linda later learns, to her horror, Heather's intentions go far beyond the mischievous.

The film centers on Dr. Marcus, a renowned psychiatrist who has selected 6 severe mentally ill and dangerous patients from the Spring Valley Mental Hospital to interview as part of research for his new book. As Dr. Marcus interviews each patient, one by one the horrors they have committed begin to unfold. However, Dr. Marcus soon learns that there is one patient who ties them all together - Patient Seven.