Marshal Kirk Reed is escorting five female prisoners---killers all--- from one part of Texas to another part of Texas where a new prison has been built. Along the way he has to deal with dissension among the troops, attacks by the Comanches, a budding romance with Ellen, The Missouri Lady, before her ex-husband, The Missouri Kid, shows up in an attempt to rescue her.

A group of nurses, doctors and nuns are taken hostage in Vietnam and sent up river to a castle hideout so they can cure an ailing war general.

A couple wash up on an uncharted island where Nazi experiments are going on.