Mimi, an orphan, is taken in by a drunken innkeeper and becomes a domestic. She meets Rudolphe, scion of a well-to-do family, who rescues her from the unwanted advances of a drunken hotel guest. They fall madly in love, but Rudolphe's uncle, M. Durandin, wants Rudolphe to marry a family friend, Madame de Rouvre, and writes Mimi a letter, telling her that she is ruining Rudolphe's life. Musette and Marcel, friends of Mimi, also try to break up the romance by introducing Mimi to other men, and Rudolphe becomes jealous and leaves her. Brokenhearted, Mimi declines in health and eventually throws herself into the river but is rescued and taken to the hospital. Realizing it is only a matter of time before she dies, she drags herself back to the room where she and Rudolphe were happiest. Rudolphe is there and she dies knowing that he loves her.

In the 50's, in Paris, the neighbors Rodolfo and Mimi meet each other when Mimi's candle blows out in a cold and dark night. They immediately fall in love for each other, in times of financial difficulties in the post-war. Rodolfo introduces Mimi to his close friends Marcello and his beloved Musetta; Colline; and Schaunard and together they have a good-time in Café Momus. Some time later, Mimi tells Marcello that she can not support the jealousy of Rodolfo any longer and when Marcello discuss with Rodolfo, Mimi overhears the real reason for the behavior of her beloved Rodolfo.