It's a night of comic anarchy as 15 of today's edgiest comedians perform at Los Angeles' legendary Troubadour rock 'n' roll club! You're guaranteed to laugh, and occasionally gasp with shock, as new comic frontiers are crossed. Staring; Patton Oswalt, Brian Posehn, Zach Galifianakis, Maria Bamford, David Cross, Sarah Silverman, and many more.

The Comedians of Comedy is an occasional stand-up comedy tour featuring Patton Oswalt, Zach Galifianakis, Brian Posehn and Maria Bamford that was documented in a 2005 film and 2005 Comedy Central television series of the same name, both directed by Michael Blieden.

The show was recorded at the San Francisco club The Purple Onion in June 2005. In addition to Zach's routine, which features Zach's trademark dry humor, a large portion of which is accompanied by a light piano piece played by Zach as bed music. It ends with Zach tearing off pages of a large pad of paper which contain prewritten, largely self deprecating jokes, while a boys choir sings Greatest Love of All. The DVD contains two separate sections which are cut to throughout the routine, often at times where the content of the routine may have to do with the content of the other portions. One of the sections is an unscripted roadtrip to The Purple Onion in a Volkswagen bus with Zach and his friend Joe Wagner. The banter and happenings that occur seem to provide insights to where Zach gets some of his comedy. The bus ends up breaking down just short of their goal so they finish the trip in rented small car, usually meant for tourists. The roadtrip portrays Zach as a fun-loving guy, different than his stage persona. The second section is a loosely scripted interview of Seth Galifianakis (played by Zach) by Brian Unger. Though Zach, himself, doesn't appear in this section but the aim of the interview seems to be to find the root of Zach's depression and ramblings on stage. The DVD was released March 6, 2007.

Galifianakis dreamed of becoming a star. But when Will Ferrell discovered his public access TV show, 'Between Two Ferns' and uploaded it to Funny or Die, Zach became a viral laughing stock. Now Zach and his crew are taking a road trip to complete a series of high-profile celebrity interviews and restore his reputation.