The mysterious appearance of the Black and White Impermanence spreads fear throughout Chang'an, prompting an investigation that reveals they are people controlled by magic.

靺鞨粟末部落狼人萨满劫杀新罗向大唐敬献之佛女，阻两国修好，不想巧遇到边境办案的狄仁杰，狄仁杰与司马小刀、段医师联手，抽丝剥茧，破获了靺鞨粟末部落阴谋，再一次拯救国家于危难。