Dennis O'Keefe, newly married to lovely Sheila Ryan, is in a jam. O'Keefe's former girl friend, exotic dancer Marie McDonald, has in her possession an expensive, jeweled garter given to her by O'Keefe in his bachelor days. McDonald intends to show the garter to O'Keefe's suspicious wife, so Our Hero must retrieve the embarrassing accouterment without tipping off the missus.

Casanova, a young patriot in 18th-century Sicily, upon learning that his father and sister have been murdered, returns to Palermo and engages in guerilla tactics against the forces of the Governor. Lady Bianca, the Governor's daughter, is in love with one of the patriots, Lorenzo, and desires to escape from the palace. Her lady-in-waiting, Zanetta, enlists the aid of Casanova and he rescues them and takes them to the partisan's camp. The rebels are victorious. Lady Bianca makes plans to marry Lorenzo, and Casanova and Zanetta have similar plans.

Two rival newspapers are engaged in a circulation battle, complicated by the fact that a vicious gangster inserts himself into the middle of it. Also complicating matters is that one newspaper's editor and circulation director are competing for the affections of a pretty blonde reporter.

Mr. Dithers is trying to encourage a businessman to build a war-time manufacturing plant on land he owns while Dagwood tries to prevent the businessman from learning his daughter is involved in a local theatre production.

Jonathan Peckinpaw feels he's failed in his patriotic duty when he's rejected by the army, but he sees a chance to redeem himself by exposing a secret ring of Nazi spies.

Cookie is born, producing unmitigated joy in the Bumstead household. Adding to the chaos a new baby always creates is the appearance of Hans Conried as a cynical author who becomes caught up in the Bumstead lifestyle.

It is the story of Gene's, a Cavalry scout, who manages to quell an Indian uprising.

When Tasker kills Roy Rogers he takes one of his young sons. Fifteen years later the other son Roy arrives buying a ranch in the valley where Tasker now controls the water supply. Roy organizes the ranchers for a showdown with Tasker not knowing that his brother is Tasker's chief henchman.

Dagwood brings home a pedigreed Great Dane which an important company client wants and which Blondie enters in the big dog show.

Mr. Dithers invites the Bumsteads on a South American cruise. Somehow Dagwood winds up as the female drummer in the ship's band, while Penny Singleton gets to show off her Broadway background in some lively musical numbers.

Treasury Department officials recruit a florist (Raft) to lead them to a wanted criminal (Macready); but once he gets too close, he finds he's the hunted.

A woman watches her own funeral, then sets out with her lawyer to learn who was in the casket.