Midlothia is a small, tight-knit town, where everyone knows everyone else's business. On Fred's last day in town, he and his closest friends uncover secrets that threaten the fabric of their friendship.

While searching for a "cure all" serum, Dr. Edward Kanopolus, "Dr. K", is being pressured for results by the pharmaceutical company funding the project. With time running out, tragedy and desperation drive him to make decisions that will jeopardize the lives of everyone around him and ultimately unleash a terrifying monster on a killing spree.

溫暖水域吸引無溝雙髻鯊靠近美國海岸，令鯊魚專家漢馬舒勒博士得以趁機研究。他跟水底攝影師祖洛梅路冒險近距離觀察這種越來越珍罕的巨大掠食者，並嘗試捕捉和追蹤牠們，以深入了解其遷徙、交配和覓食習慣。