When Charles learns that his wife and her lover want to poison him, he thinks of killing both of them.

Professor Louis Delage is a kidney transplant specialist. He is so good in his field that his peers nickname him the "great man". But one day, one of his patients die during surgery and Delage starts doubting. Is he actually such a great man? To fight desperation he decides to take in the deceased child while devoting more time to Florence, his hitherto neglected wife.

Paul Lamiani, a wizened mobster, is asked to return to duty following the disappearance of secret documents of extreme importance. It is assumed that they are in the hands of a friend of Paul. But the case becomes even more delicate when Lamiani's son is kidnapped.