Judith Fontaine is looking for her sister Joanie, who has disappeared into the hippie community of Venice, California. It turns out that Joanie has become fallen victim to Groton, an ax-wielding homicidal maniac under the employ of Dr. Durea, the last living descendant of the Frankenstein family and is now both running a house of horrors on the beach's boardwalk and performing experiments on Gorton's victims in his basement laboratory.

Sex-hungry teens are kidnapped by auto mechanics, who take them to a rural hospital run by aliens who need their blood as the key to their own longevity.

Naive, but brash and sultry teenage runaway Bonnie finds herself lost and adrift in America. The lovely young lass runs afoul of a colorful array of evil oddballs who all treat her like an object: violent criminal Pat makes Bonnie help her kidnap the middle-aged Dan Daubrey; domineering lesbian painter Geraldine Mills wants Bonnie to be her kept girl and uses her as a model; and wicked misogynistic rich sicko Vincent Stackman desires poor Bonnie as the ultimate prized possession in his menagerie of caged female animals he keeps locked up in the basement of his swanky remote mansion.