Satanists murder the owner of an experimental "rape clinic" and subject one of her patients to their own sexual perversions.

Misty and Ruby are a couple who run a lesbian bar in New Jersey when their lives change one night with the arrival of a seductive woman (Anoushka) who bites Misty, thus starting her slow transformation into a werewolf. Anoushka the werewolf returns to her home in London, England where she gives an interview to a young reporter about her life as a werewolf, while back in America, Misty undergoes a slow transformation into a werewolf herself which may lead to danger for Ruby, and any other woman involved.

Olivia, a beautiful hooker under the influence of the violent and degenerate pimp Claudio, uses her charms to seduce young women so Claudio can film them. Things take a turn for the worse when Melody, one of Olivia's willing "victims", suddenly disappears one day. Her roommate Alice fears that she may be next.