In the aftermath of the Shi Clan's rebellion, things have finally settled down, and Maomao has returned to her old life as a pharmacist in the pleasure district. One day, triggered by a breakfast served at the Verdigris House, Maomao senses an anomaly and begins investigating its true nature. Meanwhile, Jinshi, who has revealed his true identity as the Imperial brother and begun to face his heavy responsibilities, is deeply troubled by the final message left by Loulan: a warning of an impending "disaster that will strike the nation." To make matters worse, rumors of a mysterious shrine maiden who deceives the people begin to spread, casting a dark shadow over the country of Li once again. From the depths of the inner court to the city streets, and across foreign borders—the world grows wider, and the stakes even higher for Maomao and Jinshi. (Source: Crunchyroll)

Using her wit and vast knowledge of medicines and poisons alike, Maomao played a pivotal role in solving a series of mysteries and conspiracies that plagued the imperial court. Having recently come to terms with the secrets of her parents, she returns to fulfill her normal duties on behalf of the emperor's highest-ranking consorts. Maomao also works alongside the eunuch Jinshi to better the consorts' many ladies-in-waiting, including helping them learn to read. However, with the arrival of a merchant caravan comes a new wave of intrigue. A pattern of strange coincidences involving the visitors and their wares unsettles Maomao, driving her to investigate the puzzling circumstances behind the convoy. As dangers from both outside and within threaten the balance between the imperial concubines, Maomao continues to utilize her cunning and medical expertise to keep the women safe from harm. (Source: MAL Rewrite)

大陆的中央有个大国，在那个国家的后宫之中有一位少女，其名为“猫猫”。她以前在花街做药师，现在在后宫做事。某天，她得知皇子们皆早夭，而现在的两个皇子都因为生病而逐渐衰弱。于是，在好奇心的驱使下，她开始调查事情的真相，就好像在说世上不可能存在诅咒。壬氏是一位外表俊美的宦官，他让猫猫当皇帝宠妃的试毒人。猫猫对人没有兴趣，却异常钟情毒和药，就是这样一位在花街长大的药师，被卷入了宫中的传闻事件。美丽的玫瑰长有刺，女人的庭院里到处都是毒，流言和阴谋更是不缺。虽然不断地被壬氏委托麻烦事，但猫猫还是照常处理。罕见的嗜毒姑娘今天也在后宫里奔走。

本作がより楽しめるミニアニメ「猫猫のひとりごと」の配信が決定！ TOHO animation公式YouTubeチャンネル、『薬屋のひとりごと』公式TikTokにて配信！ ミニアニメ「猫猫のひとりごと」は、各エピソードに登場したキーアイテムの解説を猫猫がする各話の後日譚となっています。 ちびキャラになった猫猫と壬氏の本編では見ることのできないやり取り、エピソードにもご注目ください。「猫猫のひとりごと」第1話～３話は、23日（月）正午12時より配信開始。 第4話以降は放送後月曜日正午12時に更新されていくのでお楽しみに！ 詳しくは公式サイトのMOVIEページをご確認ください。

With Hell overwhelmed by an exploding population of sinners, bureaucrat Hozuki works diligently to keep the flames of punishment burning on time.

留着黑长发、浑身散发着阴森气息、被称为“贞子”的高中少女黑沼爽子（能登麻美子 配音），在爽朗少年风早翔太（浪川大辅 配音）的帮助下，她不仅交到了两个好朋友矢野绫音（泽城美雪 配音）和吉田千鹤（三瓶由布子 配音），本性善良温柔的她也开始慢慢融入了班集体。第一季中，她已经开始 意识到自己喜欢风早，生性腼腆胆小的她却迟迟不敢向风早告白。 第二季的故事从一份没有送出去的情人节礼物开始，迎来新学期的爽子和风早，能否勇敢面对彼此之间的感情？升入二年级的他们，还迎来了一位新同学三浦健人。爽子、风早、绫音、千鹤和龙也，由他们谱写的校园纯爱故事，在第二季中延续着…… 本动画改编自椎名轻穗同名漫画作品。原作现正在别册玛格丽特上连载，是单行本销售总数已突破1000万部的超人气少女向作品。