Shortly after a hurtful breakup, Diane, a transgender pagan priestess, finds refuge in Palm Springs. She is engaged in a battle with her inner demons when an enigmatic sociopath, starts to stalk her.

It's a hot summer day in June, 1969. Marsha throws herself a birthday party and dreams of performing at a club in town, but no one shows up. Sylvia, Marsha’s best friend, distraught from an unsuccessful introduction between her lover and her family, gets so stoned she forgets about the party. Marsha, Sylvia, and friends eventually meet at the Stonewall Inn to celebrate Marsha's birth. When the police arrive to raid the bar, Marsha and Sylvia are among the first to fight back.

It's Christmas Eve in Tinseltown and Sin-Dee is back on the block. Upon hearing that her pimp boyfriend hasn't been faithful during the 28 days she was locked up, the working girl and her best friend, Alexandra, embark on a mission to get to the bottom of the scandalous rumor. Their rip-roaring odyssey leads them through various subcultures of Los Angeles, including an Armenian family dealing with their own repercussions of infidelity.