Eve Simonswas abandoned as an infant on the steps of a church 30 years ago on Christmas Eve. Now, struggling to move forward with her life, she embarks on a search to uncover the mystery of her birth with the help of her boyfriend Chris and famed investigative genealogist Pamela Slaton.

When loser Duke, who has screwed up every hair-brained scheme he's ever come up with, accidentally falls off a cruise ship and wakes up on a mysteriously abandoned, top secret government island, he discovers that it's overrun with mutants and monsters from a failed 1980s DARPA "super soldier" project to stop the 2nd Cold War.

Rookie police officer Jessica Loren has been assigned the last shift at a closing police station and must wait for a hazmat crew to collect biomedical evidence. Ordered not to leave the station under any circumstances, Jessica comes to learn that it's more than just an outdated station, it's home to the ultimate embodiment of evil and his devoted bloodthirsty followers. Jessica is left to fend for herself in the Devil's playground.