Andrea (Riccardo Maria Manera) is a young man who lives with the surprises and hardships of life. He lives with his best friend, seeks to complete his studies and has an ex-girlfriend who plays with him like cat and mouse. When he discovers that he has an incurable disease, the world collapses on him. Can an illness change a person's life... for the better? Thanks to Giulia (Jenny De Nucci), Andrea will understand that the time has come to assume what remains of her own existence.

Lino and Chicca are an aging, childless middle-class couple whose life is disrupted after he's diagnosed with Alzheimer's disease.

罗伯特（Roberto Ciufoli 饰）童年时曾经目击过一起凶杀案，他并没有看清凶手的长相，只知道凶手穿了一双黄色皮鞋，这成为了罗伯特一生的阴影。长大之后，罗伯特成为了一名甜品师。一天，姑妈告诉罗伯特，自己准备将所有的财产都留给他，但有一个条件，那就是罗伯特要在她100岁的生日当天在公爵剧院举办一场演出。这并不是一件轻松的差事，因为公爵剧院正是罗伯特幼年时目击凶案的地方，它因此而倒闭，一直到25年后的今天依然无人问津。 为了钱，罗伯特打算拼了。他选定了《哈姆雷特》为表演剧目，并且开始着手排练和打扫剧院。哪知道在此过程中，再次发生了命案。