While trapped on the island of Madagascar, the Central Park Zoo escapees receive a visit from Santa--crash landing on their territory and getting amnesia to boot! The animals must help Santa assume his rightful place in the universe, while King Julian laps up the opportunity for his subjects.

Alex, Marty, and other zoo animals find a way to escape from Madagascar when the penguins reassemble a wrecked airplane. The precariously repaired craft stays airborne just long enough to make it to the African continent. There the New Yorkers encounter members of their own species for the first time. Africa proves to be a wild place, but Alex and company wonder if it is better than their Central Park home.

Four animal friends get a taste of the wild life when they break out of captivity at the Central Park Zoo and wash ashore on the island of Madagascar.