A group of space renegades hook up with a drifter named McQueen. Together they hole up in an abandoned research facility for the night and are relentlessly pursued by a human/monster hybrid.

In the future, humans are divided into Sex Negatives and Sex Positives. The negatives get sick if they have sex so they go to Cafe Flesh to see positives who are forced to perform on stage for the negatives. Lana is a positive who everyone thinks is a negative and she must decide whether to come clean or not.