After discovering her father put their house up for his bail bond and then disappeared, 17-year-old Ree Dolly must confront the local criminal underworld and the harsh Ozark wilderness in order to to track down her father and save her family.

After seven months have passed without a culprit in her daughter's murder case, Mildred Hayes makes a bold move, painting three signs leading into her town with a controversial message directed at Bill Willoughby, the town's revered chief of police. When his second-in-command Officer Jason Dixon, an immature mother's boy with a penchant for violence, gets involved, the battle between Mildred and Ebbing's law enforcement is only exacerbated.