Series 11 follows the Thirteenth Doctor as she initially searches for her lost TARDIS, inadvertently bringing Graham, Ryan, and Yasmin with her on her travels. All three later contemplate returning to their normal lives but decide to continue travelling with the Doctor.

The series follows the Thirteenth Doctor and her companions as they meet a new incarnation of the Master, and his destruction of Gallifrey, the return of Jack Harkness, the appearance of an unknown incarnation of the Doctor, the Cybermen, and the secret of the "Timeless Child". Jodie Whittaker returns for her second series as the Thirteenth Doctor. It also stars Bradley Walsh, Tosin Cole and Mandip Gill as the Doctor's travelling companions, playing Graham O'Brien, Ryan Sinclair and Yasmin Khan, respectively.