泡沫经济时期（1992年），背负着悲惨过去的庆应大学毕业生半泽直树如愿进入产业中央银行就职。银行内部有着“旧东京”与“旧产业”派系斗争。这一年，半泽直树就任东京中央银行大阪西分行融资课课长已有两年。坚信人性本善的他在履行银行家职责的同时坚守着普世的道义。半泽能否凭一己之力改变这冷漠腐化的现状？他能否对抗银行内外的敌人、贯彻自己的信念？

Mikio is a married man and works hard for the company where he is employed. Then one day Mikio is diagnosed with depression. Mikio's wife is Haruko. They have been married for 5 years. Haruko draws comics for work, but they do not sell well. She mainly relied on Mikio for support. Meanwhile, Haruko did not notice any changes in her husband. She begins to blame herself for not noticing any signs. Mikio's depression derived from his work. His company has been pressing him to quit the company. After Mikio quits his job his condition improves, but the dynamics of their relationship changes.

When easy-going Aoyagi meets an old friend for a fishing trip, he ends up drugged, framed for the Prime Minister's assassination, and on the run from corrupt cops. It's only the beginning of what quickly becomes the worst, weirdest day of his life. But he'll get by with a little help from his friends, who include a famous pop diva, a rockabilly deliveryman, a crippled old gangster, and the world's most cheerful serial killer.