Sara and Brian live an idyllic life with their young son and daughter. But their family is rocked by sudden, heartbreaking news that forces them to make a difficult and unorthodox choice in order to save their baby girl's life. The parents' desperate decision raises both ethical and moral questions and rips away at the foundation of their relationship. Their actions ultimately set off a court case that threatens to tear the family apart, while revealing surprising truths that challenge everyone's perceptions of love and loyalty and give new meaning to the definition of healing.

安娜的姐姐凯特两岁时罹患严重的急性早幼粒细胞白血病，安娜的父母为了给凯特治病，通过先进的基因技术孕育并生下了与凯特的基因完美配型的小女儿安娜。从第一管脐带血开始，十三年来，安娜不断地向凯特捐献出脐带血、白血球、干细胞、骨髓……现在，凯特的肾功能衰竭，父母要求安娜捐献一个肾脏给姐姐。 无法忍受再被当成药量的安娜决定反击她的父母。 安娜在报上看到律师坎贝尔的信息，她卖掉爸爸送给自己的金项链，在哥哥杰西的帮助下找到律师事务所，请求坎贝尔做她的律师，她要控告自己的父母，控告他们夺走她的身体使用权。