本作是家用机版《真三国无双6》的移植版，在游戏中除了保持既有要素之外，还将追加适合掌机的多人联机要素以及全新要素，其中多人要素包括故事模式以及编年史模式可以进行双人并肩作战，以及使用资金购买成长物品。 　　游戏中还保持原版故事模式的视频，除了既有的“魏”“蜀”“吴”三国武将的战史之外，全新追加的“晋”武将的故事也是不容错过的。

In the year 198, Cao Cao, Prime Minister of the Han Dynasty, ventured to the east and defeated China's greatest warrior Lu Bu, terrifying every ambitious warlord across the country. Several years later, after taking the Han Emperor under his wing, Cao crowns himself King of Wei. He built a magnificent Bronze Sparrow Island to symbolize his power and rumors spread that he would replace the Emperor. Meanwhile, young lovers Mu Shun and Ling Ju are taken from a prison camp to a hidden tomb, where they spend five cruel years together, training as assassins for a secret mission. In the year 220 astronomical signs predict dramatic change. As a result, Cao's son Cao Pi and Cao's followers urge Cao to become the new Emperor - but unknown opposing forces plot against him.