Universal Century 0079. Humanity has turned even space itself into a battlefield, and the Principality of Zeon forces advance after wiping out half the world's population by carrying out the Operation British (colony drop). In response, the Earth Federation Forces mobilize their overwhelming fighting strength to regain the advantage. The complex intrigues of the Zabi family... Sayla Mass, as she contends with the whims of fate... Hamon and Ramba Ral, who is now a pilot in the Zeon forces... Amuro and Fraw, leading peaceful lives at Side 7... a dark shadow falls across them all. And the Zeon ace Char Aznable, driven by revenge, goes into action as the "Battle of Loum" finally begins.

After Colony (A.C.) 195. Mankind has moved into space. Thousands of people live on giant orbiting space colonies called "Sides." However, the Earth Government, which rules the colonies, is unjust and cruel. A group of revolutionaries builds five robotic weapons called Gundams and plans to send them to Earth to begin their fight for independence. Piloted by five young men, these Gundams carry the hopes and dreams of freedom of the colonists with them as they descend to Earth to begin Operation Meteor!

U.C. 0096, three years after the end of the Second Neo Zeon War. The mysterious Vist Foundation attempts to hand over a certain secret to the Neo Zeon remnants known as the Sleeves. This will mean the opening of Laplace's Box, which holds a great secret tied to the origins of the Universal Century. The exchange is to take place at the manufacturing colony Industrial 7, home of the student Banagher Links. When Banagher rescues a girl who gives her name as Audrey Burne, he is drawn into the conflict surrounding Laplace's Box.