In the deep south during the 1930s, three escaped convicts search for hidden treasure while a relentless lawman pursues them. On their journey they come across many comical characters and incredible situations. Based upon Homer's 'Odyssey'.

It is 1967, and Larry Gopnik, a physics professor at a quiet Midwestern university, has just been informed by his wife Judith that she is leaving him. She has fallen in love with one of his more pompous acquaintances Sy Ableman.