As America's stock of athletic young men is depleted during World War II, a professional all-female baseball league springs up in the Midwest, funded by publicity-hungry candy maker Walter Harvey. Competitive sisters Dottie Hinson and Kit Keller spar with each other, scout Ernie Capadino and grumpy has-been coach Jimmy Dugan on their way to fame.

A cop who loses his partner in a shoot-out with gun smugglers goes on a mission to catch them. In order to get closer to the leaders of the ring he joins forces with an undercover cop who's working as a gangster hitman. They use all means of excessive force to find them.