The Bride unwaveringly continues on her roaring rampage of revenge against the band of assassins who had tried to kill her and her unborn child. She visits each of her former associates one-by-one, checking off the victims on her Death List Five until there's nothing left to do … but kill Bill.

A burger-loving hit man, his philosophical partner, a drug-addled gangster's moll and a washed-up boxer converge in this sprawling, comedic crime caper. Their adventures unfurl in three stories that ingeniously trip back and forth in time.