The fourth series begins with the nation’s favourite detective, the mercurial Sherlock Holmes, back once more on British soil, as Doctor Watson and his wife, Mary, prepare for their biggest ever challenge - becoming parents for the first time.

Patrick Melrose is a man from a very privileged yet traumatic childhood in the 1980s. Patrick's father was a very abusive man and Patrick's mother put up with his behavior. Eventually, Patrick's trauma led him down a path of adulthood addiction and severe substance abuse in New York.