Mikio is a married man and works hard for the company where he is employed. Then one day Mikio is diagnosed with depression. Mikio's wife is Haruko. They have been married for 5 years. Haruko draws comics for work, but they do not sell well. She mainly relied on Mikio for support. Meanwhile, Haruko did not notice any changes in her husband. She begins to blame herself for not noticing any signs. Mikio's depression derived from his work. His company has been pressing him to quit the company. After Mikio quits his job his condition improves, but the dynamics of their relationship changes.

本田透（堀江由衣 配音）是一名单纯善良的女子高中生。母亲过世后，无处可去的她在误打误撞之中住进了校草草摩由希（久川绫 配音）的家中。草摩由希家里有十二口人，很快，本田透就发现了他们身上的秘密。原来，草摩家族里流传着一个诅咒，那就是他们每个人都对应着十二生肖里的一种动物，另外一个，则是猫妖。 个性冷淡，非常内向的草摩夹（关智一 配音）、幽默风趣的草摩紫吴（置鲇龙太郎 配音）、活泼可爱积极乐观的草摩红叶（斋藤彩夏 配音）、有着复杂过去的草摩波鸟（井上和彦 配音），在知道了这些表面开朗的人们背后隐藏的伤痛后，本田透会怎样给予治愈呢？