A secret military project endangers Neo-Tokyo when it turns a biker gang member into a rampaging psychic psychopath that only two teenagers and a group of psychics can stop.

Cyborg detective Batou is assigned to investigate a series of murders committed by gynoids—doll-like cyborgs, which all malfunctioned, killed, then self-destructed afterwards. The brains of the gynoids initialize in order to protect their manufacturer's software, but in one gynoid, which Batou himself neutralized, one file remains: a voice speaking the phrase "Help me."

When 17-year-old Makoto Konno gains the ability to, quite literally, "leap" backwards through time, she immediately sets about improving her grades and preventing personal mishaps. However, she soon realises that changing the past isn't as simple as it seems, and eventually, will have to rely on her new powers to shape the future of herself and her friends.

A young witch, on her mandatory year of independent life, finds fitting into a new community difficult while she supports herself by running an air courier service.

Three moments in Takaki's life: his relationship with Akari and their forced separation; his friendship with Kanae, who is secretly in love with him; the demands and disappointments of adulthood, an unhappy life in a cold city.