Betrayed by Vesper, the woman he loved, 007 fights the urge to make his latest mission personal. Pursuing his determination to uncover the truth, Bond and M interrogate Mr. White, who reveals that the organization that blackmailed Vesper is far more complex and dangerous than anyone had imagined.

Le Chiffre, a banker to the world's terrorists, is scheduled to participate in a high-stakes poker game in Montenegro, where he intends to use his winnings to establish his financial grip on the terrorist market. M sends Bond—on his maiden mission as a 00 Agent—to attend this game and prevent Le Chiffre from winning. With the help of Vesper Lynd and Felix Leiter, Bond enters the most important poker game in his already dangerous career.

When Bond's latest assignment goes gravely wrong, agents around the world are exposed and MI6 headquarters is attacked. While M faces challenges to her authority and position from Gareth Mallory, the new Chairman of the Intelligence and Security Committee, it's up to Bond, aided only by field agent Eve, to locate the mastermind behind the attack.