故事发生在一座风景秀丽的小岛之上，古森太郎（小野贤章 配音）、中岛匡幸（福山润 配音）和大神信（保志总一朗 配音）是生活在这里的三位少年，每个人都有一段不愿意回忆的悲伤过往。
某日，厌倦了一成不变无聊生活的三人聚集到了一起，前往传说中的诅咒之地探险，在“现世”和“幽世”的交接处，三人目睹了十分恐怖而又充满了痛苦的景象。恐惧之中，三人匆忙逃跑，却发现灵魂竟然脱离了肉体，当他们再度找回肉身之后，一切都改变了，三人获得了自由穿梭于两个世界的特异功能。与此同时，古森太郎曾经遭遇过的绑票事件的真相重新浮出了水面。

The year is 2030 and six years have passed since a criminal known only as "The Laughing Man" swept through top medical nanotechnology firms committing acts of cyber-terrorism, kidnapping, and espionage leaving no known suspects. New information is revealed, as Section 9 enters the hunt for a suspect capable of unfathomable actions in this compilation of Stand Alone Complex content.

In 2030 AD, even if the intention to run around as light and electrons is concentrated in one direction as the computerization becomes generalized and the information network becomes more sophisticated, by the time the "lonely person" becomes an "individual" as a complex. Is an era when it is not computerized. It depicts the activities of the "Public Security Section 9" (commonly known as "Ghost in the Shell"), which was established as an independent counterintelligence unit under the direct control of the Ministry of Home Affairs to counter complicated crimes. There are a wide variety of top-secret missions such as cybercrime investigation, terrorism deterrence / arrest, VIP protection, and corruption detection, but one incident emerges as it is carried out.